I-Anti- human s100 β Antibody, iMonoclonal yeMouse
Iinkcukacha zemveliso
Iinkcukacha zajikelele
I-S100B yiprotheyini ebopha i-calcium, ekhutshelwa kwii-astrocytes.Yiprotheni encinci ye-dimeric cytosolic (21 kDa) equkethe i-ββ okanye i-αβ chain.I-S100B ibandakanyeka kwimisebenzi eyahlukeneyo yokulawula i-intracellular kunye ne-extracellular.
Kule minyaka ilishumi idlulileyo, i-S100B iye yavela njengomgqatswa we-peripheral biomarker yomonakalo we-blood-brain barrier (BBB) kunye nokulimala kwe-CNS.Amanqanaba aphezulu e-S100B abonisa ngokuchanekileyo ubukho beemeko ze-neuropathological ezibandakanya ukulimala kwentloko ebuhlungu kunye nezifo ze-neurodeergenerative.Amanqanaba aqhelekileyo e-S100B awabandakanyi i-CNS pathology enkulu.I-Serum S100B nayo iye yaxelwa njengesixhobo esiluncedo ekubhaqweni kwangaphambili kwe-metastases ye-melanoma kunye neengxaki ze-cerebral ezivela entloko, utyando lwentliziyo, kunye ne-stroke ebukhali.
Iipropati
| Izindululo ezimbini | I-CLIA (Thatha-Ukufunyanwa): 5H2-3 ~ 22G7-5 22G7-5 ~ 5H2-3 |
| Ubunyulu | >95% njengoko kumiselwe yiSDS-PAGE. |
| Ukuqulunqwa kwesithinteli | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
| Ugcino | Yigcine phantsi kweemeko ezingakhuselekanga ku -20℃ ukuya -80℃ xa uyifumene. Ncoma ukuba i-aliquot iprotheni ibe yimiyinge emincinci yokugcina eyona ilungileyo. |
Uthelekiso lokukhuphisana
Ulwazi lweodolo
| Igama lemveliso | Ikati.Hayi | Clone ID |
| s100 β | AB0061-1 | 5H2-3 |
| AB0061-2 | 22G7-5 | |
| AB0061-3 | 21A6-1 |
Qaphela: I-Bioantibody inokuhlengahlengiswa ngokwemfuno yakho.
Ucaphulo
1. Ostendorp T , Leclerc E , Galicet A , et al.Ingqiqo yesakhiwo kunye nokusebenza kwi-RAGE isebenze nge-multimeric S100B [J].I-EMBO Journal, 2007, 26 (16): 3868-3878.
2. R, D, Rothoerl, et al.Amanqanaba aphezulu e-serum ye-S100B kwizigulane zokwenzakala ngaphandle kokulimala entloko.[J].I-Neurosurgery, ngo-2001.
