I-Anti-Human GDF15 Antibody, Monoclonal yeMouse
Iinkcukacha zemveliso
Iinkcukacha zajikelele
I-Growth-differentiation factor 15 (GDF15), eyaziwa nangokuthi i-MIC-1, ilungu elifihlakeleyo le-transforming growth factor (TGF) -β superfamily, njengenoveli ye-antihypertrophic regulatory factor in heart.I-GDF-15 / GDF15 ayichazwanga kwintliziyo yomntu omdala eqhelekileyo kodwa ibangelwa kwiimeko ezikhuthaza i-hypertrophy kunye ne-dilated cardiomyopathy kwaye ibonakaliswe kakhulu esibindi.I-GDF-15 / GDF15 inendima ekulawuleni iindlela ezivuthayo kunye ne-apoptotic kwizicubu ezonzakeleyo kunye nangexesha leenkqubo zesifo.I-GDF-15 / GDF15 idityaniswe njengeemolekyuli ze-precursor ezicutshungulwa kwindawo ye-dibasic cleavage ukukhulula imimandla ye-C-terminal equlethe i-motif ye-7 egciniweyo ye-cysteines kwiprotheni ekhulileyo.I-GDF-15 / GDF15 i-overexpression ephuma kwi-erythroid compartment eyandisiweyo inegalelo kwi-iron overload kwi-thalassemia syndromes ngokuvimbela ukubonakaliswa kwe-hepcidin.
Iipropati
| Izindululo ezimbini | I-CLIA (Thatha-Ukufunyanwa): 23F1-5 ~ 6C1-9 23F1-5 ~ 3A2-1 |
| Ubunyulu | >95%, igqitywe yiSDS-PAGE |
| Ukuqulunqwa kwesithinteli | PBS, pH7.4. |
| Ugcino | Yigcine phantsi kweemeko ezingakhuselekanga ku -20℃ ukuya -80℃ xa uyifumene. Ncoma ukuba i-aliquot iprotheni ibe yimiyinge emincinci yokugcina eyona ilungileyo. |
Uthelekiso lokukhuphisana
Ulwazi lweodolo
| Igama lemveliso | Ikati.Hayi | Clone ID |
| GDF-15 | AB0038-1 | 3A2-1 |
| AB0038-2 | 23F1-5 | |
| AB0038-3 | 6C1-9 | |
| AB0038-4 | 4D5-8 |
Qaphela: I-Bioantibody inokuhlengahlengiswa ngokwemfuno yakho.
Ucaphulo
1.Wollert KC , Kempf T , Peter T , et al.Ixabiso lePrognostic ye-Growth-Differentiation Factor-15 kwizigulane ezine-Non-ST-Elevation Acute Coronary Syndrome[J].Ukujikeleza, 2007, 115 (8): 962-971.
2.Kempf T, Haehling SV, Peter T, et al.Uncedo oluqikelelweyo lokwahlulahlula ukukhula-15 kwizigulana ezinokusilela kwentliziyo okungapheliyo.[J].Umbhalo we-American College of Cardiology, 2007, 50 (11): 1054-1060.
