Anti-human VEGF Antibody, Monoclonal Mouse
Iinkcukacha zemveliso
Iinkcukacha zajikelele
I-Vascular endothelial growth factor (VEGF), eyaziwa ngokuba yi-vascular permeability factor (VPF) kunye ne-VEGF-A, ngumlamli onamandla we-angiogenesis kunye ne-vasculogenesis kwi-fetus kunye nomntu omdala.Lilungu le-platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) intsapho kwaye ihlala ikhona njenge-homodimer edibeneyo ne-disulfide.I-VEGF-A iprotheni yi-mitogen ye-glycosylated esebenza ngokuthe ngqo kwiiseli ze-endothelial kwaye ineempembelelo ezahlukeneyo, kuquka ukulamla ukunyuka kwe-vascular permeability, i-inducing angiogenesis, i-vasculogenesis kunye ne-endothelial cell growth, ukukhuthaza ukufuduka kweeseli, ukuvimbela i-apoptosis kunye nokukhula kwethumba.Iprotheyini ye-VEGF-A ikwayi-vasodilator eyandisa i-microvascular permeability, ngenxa yoko yayibizwa ngokuba yi-vascular permeability factor.
Iipropati
| Izindululo ezimbini | I-CLIA (Thatha-Ukufunyanwa): 12A4-7 ~ 5F6-2 2B4-6 ~ 5F6-2 |
| Ubunyulu | >95%, igqitywe yiSDS-PAGE |
| Ukuqulunqwa kwesithinteli | PBS, pH7.4. |
| Ugcino | Yigcine phantsi kweemeko ezingakhuselekanga ku -20℃ ukuya -80℃ xa uyifumene. Ncoma ukuba i-aliquot iprotheni ibe yimiyinge emincinci yokugcina eyona ilungileyo. |
Uthelekiso lokukhuphisana
Ulwazi lweodolo
| Igama lemveliso | Ikati.Hayi | Clone ID |
| VEGFA | AB0042-1 | 2B4-6 |
| AB0042-2 | 12A4-7 | |
| AB0042-3 | 5F6-2 |
Qaphela: I-Bioantibody inokuhlengahlengiswa ngokwemfuno yakho.
Ucaphulo
1.Tammela T , Enholm B , Alitalo K , et al.Ibhayoloji ye-vascular endothelial growth factor[J].Uphando lwe-Cardiovascular, i-2005, i-65 (3): 550.
2.Wolfgang, Lieb, Radwan, et al.I-Vascular endothelial factor growth, i-receptor yayo enyibilikayo, kunye ne-hepatocyte factor growth: iklinikhi kunye ne-genetic correlates kunye nokudibanisa nomsebenzi we-vascular.[J].Ijenali yentliziyo yaseYurophu, ngo-2009.
