Anti-human RBP4 Antibody, Monoclonal Mouse
Iinkcukacha zemveliso
Iinkcukacha zajikelele
I-Retinol-binding protein 4 (RBP4) yi-carrier ethile ye-retinol (eyaziwa nangokuthi i-vitamin A), kwaye inoxanduva lokuguqulwa kwe-retinol engazinzanga kunye ne-insoluble kwisisombululo samanzi kwi-complex ezinzile kunye ne-soluble kwi-plasma ngokusebenzisana kwabo okuqinileyo.Njengelungu le-lipocalin superfamily, i-RBP4 equkethe i-β-barrel isakhiwo kunye ne-cavity echazwe kakuhle ifihliwe kwisibindi, kwaye ihambisa i-retinol kwiivenkile zesibindi ukuya kwizicubu ze-peripheral.Kwiplasma, i-RBP4-retinol complex isebenzisana ne-transthyretin (TTR), kwaye oku kubopha kubalulekile ekuthinteleni i-RBP4 excretion ngokusebenzisa i-glomeruli yezintso.I-RBP4 echazwe kumthombo we-ectopic ihambisa i-retinol ngokufanelekileyo emehlweni, kwaye ukusilela kwayo kuchaphazela umbono wasebusuku kakhulu.Kungekudala, i-RBP4 njenge-adipokine, ifunyenwe ukuba ibonakaliswe kwizicubu ze-adipose kwaye ihambelana nokukhuluphala, ukumelana ne-insulin (IR) kunye nohlobo lwe-2 yeswekile (T2DM).
Iipropati
| Izindululo ezimbini | I-CLIA (Thatha-Ukufunyanwa): 9D11-8 ~ 3D4-1 3C8-1 ~ 3D4-1 |
| Ubunyulu | >95% njengoko kumiselwe yiSDS-PAGE. |
| Ukuqulunqwa kwesithinteli | PBS, pH7.4. |
| Ugcino | Yigcine phantsi kweemeko ezingakhuselekanga ku -20℃ ukuya -80℃ xa uyifumene. Ncoma ukuba i-aliquot iprotheni ibe yimiyinge emincinci yokugcina eyona ilungileyo. |
Uthelekiso lokukhuphisana
Ulwazi lweodolo
| Igama lemveliso | Ikati.Hayi | Clone ID |
| RBP4 | AB0032-1 | 9D11-8 |
| AB0032-2 | 3C8-1 | |
| AB0032-3 | 3D4-1 | |
| AB0032-4 | 1C6-1 |
Qaphela: I-Bioantibody inokuhlengahlengiswa ngokwemfuno yakho.
Ucaphulo
1.Aiwei YB , Vijayalakshmi V , Bodles AM , et al.I-Retinol ibophelela iprotheyini yesi-4 ebantwini: ubudlelwane nokumelana ne-insulin, ukudumba, kunye nokusabela kwi-pioglitazone.[J].J Clin Endocrinol Metab (7): 2590-2597.
2.Haider DG , Karin S , Gerhard P , et al.I-Serum retinol-binding protein 4 iyancitshiswa emva kokwehla kobunzima kwizifundo ezityebe ngokugqithisileyo.[J].Ijenali yeClinical Endocrinology & Metabolism (3): 1168-71.
