Anti-human PGI Antibody, Monoclonal Mouse
Iinkcukacha zemveliso
Iinkcukacha zajikelele
I-Pepsinogen I, i-precursors ye-pepsin, iveliswa yi-gastric mucosa kwaye ikhutshwe kwi-lumen yesisu kunye nokujikeleza kwe-peripheral.I-Pepsinogen iqulethe ikhonkco enye ye-polypeptide ye-375 amino acids kunye ne-avareji ye-molecular weight ye-42 kD.I-PG I (isoenzyme 1-5) ifihliwe ngokukodwa ngamaseli ayintloko kwi-mucosa ye-fundac, kanti i-PG II (isoenzyme 6-7) ikhutshwe ngamadlala e-pyloric kunye ne-proximal duodenal mucosa.
I-Precursor ibonisa amanani eeseli zesisu kunye neeseli zamadlala, kwaye ihlola i-gastric atrophy ngokungathanga ngqo.Kananjalo bazinzile ngendlela engaqhelekanga ngenxa yokuba benza umsebenzi wabo phantsi kweemeko ezinzima ezikhoyo kwinkqubo yokwetyisa.I-atrophy ye-corpus mucosa ikhokelela ekuhlanganiseni okuphantsi kwe-pepsinogen I kwaye ngoko ke ukukhululwa kwayo okuphantsi kwi-serum.I-Serum pepsinogen I ibonisa umsebenzi kunye neemeko ze-gastric mucosa.
Iipropati
| Izindululo ezimbini | I-CLIA (Thatha-Ukufunyanwa): 1C1-3 ~ 1G7-3 1E3-1 ~ 1G7-3 |
| Ubunyulu | >95%, igqitywe yiSDS-PAGE |
| Ukuqulunqwa kwesithinteli | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
| Ugcino | Yigcine phantsi kweemeko ezingakhuselekanga ku -20℃ ukuya -80℃ xa uyifumene. Ncoma ukuba i-aliquot iprotheni ibe yimiyinge emincinci yokugcina eyona ilungileyo. |
Uhlalutyo lokuthelekisa
Ulwazi lweodolo
| Igama lemveliso | Ikati.Hayi | Clone ID |
| PGI | AB0005-1 | 1C1-3 |
| AB0005-2 | 1E3-1 | |
| AB0005-3 | 1G7-3 |
Qaphela: I-Bioantibody inokuhlengahlengiswa ngokwemfuno yakho.
Ucaphulo
1.Sipponen P , Ranta P , Helske T , et al.Amanqanaba eSerum ye-amidated gastrin-17 kunye ne-pepsinogen I kwi-atrophic gastritis: uphononongo lolawulo lwemeko yoqwalaselo.[J].I-Scandinavian Journal ye-Gastroenterology, i-2002, i-37 (7): 785-791.
2.Mangla JC , Schenk EA , Desbaillets L , et al.Ukukhutshwa kwe-pepsin, i-pepsinogen, kunye ne-gastrin kwi-Barrett's esophagus'.Iimpawu zeklinikhi kunye ne-morphological[J].I-Gastroenterology, i-1976, i-70 (5 PT.1): 669-676.
