Anti-human AFP Antibody, Monoclonal Mouse
Iinkcukacha zemveliso
Iinkcukacha zajikelele
I-Alpha-fetoprotein (AFP) ihlelwa njengelungu le-albuminoid gene superfamily equkethe i-albumin, i-AFP, i-vitamin D (Gc) protein, kunye ne-alpha-albumin.I-AFP yi-glycoprotein ye-591 amino acids kunye ne-carbohydrates moiety.I-AFP yenye yeeprotheyini ezininzi ze-embryo-specific kwaye iyiprotein ye-serum elawulayo kwasekuqaleni kubomi be-embryonic yomntu njengenyanga enye, xa i-albumin kunye ne-transferrin zikhona ngexabiso elincinci.Iqala idityaniswe emntwini ngesingxobo se-yolk kunye nesibindi (iinyanga ezi-1-2) kwaye emva koko ikakhulu esibindini.Umlinganiselo omncinci we-AFP uveliswa yi-GI tract ye-conceptus yomntu.Kuye kwangqinwa ukuba i-AFP inokuphinda ivele kwi-serum kwixabiso eliphakamileyo kubomi bomntu omdala ngokubambisana neenkqubo eziqhelekileyo zokubuyisela kunye nokukhula okubi.I-Alpha-fetoprotein (AFP) luphawu oluthile lwe-hepatocellular carcinoma (HCC), i-teratoblastomas, kunye ne-neural tube defect (NTD).
Iipropati
| Izindululo ezimbini | I-CLIA (Thatha-Ukufunyanwa): 3C8-6 ~ 11D1-2 8A3-7 ~ 11D1-2 |
| Ubunyulu | >95%, igqitywe yiSDS-PAGE |
| Ukuqulunqwa kwesithinteli | PBS, pH7.4. |
| Ugcino | Yigcine phantsi kweemeko ezingcolileyo kwi -20℃ukuya kwi-80℃ekufumaneni. Ncoma ukuba i-aliquot iprotheni ibe yimiyinge emincinci yokugcina eyona ilungileyo. |
Uhlalutyo lokuthelekisa
Ulwazi lweodolo
| Igama lemveliso | Ikati.Hayi | Clone ID |
| AFP | AB0069-1 | 11D1-2 |
| AB0069-2 | 3C8-6 | |
| AB0069-3 | 8A3-7 |
Qaphela: I-Bioantibody inokuhlengahlengiswa ngokwemfuno yakho.
Ucaphulo
1.Mizejewski GJ.(2001) I-Alpha-fetoprotein Ulwakhiwo kunye noMsebenzi: Ukufaneleka kwii-Isoforms, ii-Epitopes, kunye ne-Conformational Variants.Exp Biol Med.226(5): 377-408.
2.Tomasi TB, et al.(1977) Ulwakhiwo kunye noMsebenzi we-Alpha-Fetoprotein.Uphononongo loNyaka lwaMayeza.28: 453-65.
3.Leguy MC, et al.(2011) Uvavanyo lwe-AFP kwi-amniotic fluid: ukuthelekiswa kweendlela ezintathu ezizenzekelayo.Ann Biol Clin.69(4): 441-6.
