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Anti-human Her2 Antibody, Monoclonal Mouse

Inkcazelo emfutshane:

Ukusulungekiswa I-Affinity-chromatography I-Isotype /
Iintlobo zomamkeli Impuku Iintlobo ze-Antigen Umntu
Isicelo I-ChemiluminescentImmunoassay (CLIA)/ Immunochromatography (IC)

Iinkcukacha zeMveliso

Iithegi zeMveliso

Iinkcukacha zemveliso

Iinkcukacha zajikelele
I-Human epidermal growth factor receptor 2 (HER2), eyaziwa ngokuba yi-ErbB2, NEU, kunye ne-CD340, luhlobo lwe-membrane ye-membrane ye-glycoprotein kwaye iyingxenye ye-epidermal growth factor (EGF) yosapho lwe-receptor.Iprotheyini ye-HER2 ayinakubopha izinto zokukhula ngenxa yokunqongophala kwe-ligand binding domain yayo kunye ne-autoinhibited constitutively.Nangona kunjalo, i-HER2 yenza i-heterodimer kunye namanye amalungu osapho lwe-EGF ye-receptor ye-ligand, ngoko ke izinza i-ligand ibophe kwaye ikhulise ukusebenza kwe-kinase-mediated ye-molecules ezantsi.I-HER2 idlala indima ephambili kuphuhliso, ukwanda kweeseli kunye nokwahlulahlula.I-HER2 yofuzo iye yaxelwa ukuba idibanise ne-malignancy kunye ne-prognosis embi kwii-carcinomas ezininzi, kuquka isifuba, i-prostate, i-ovarian, i-cancer ye-lung njalo njalo.

Iipropati

Izindululo ezimbini I-CLIA (Thatha-Ukufunyanwa):
14-2 ~ 15-6
15-6~ 2-10
Ubunyulu >95%, igqitywe yiSDS-PAGE
Ukuqulunqwa kwesithinteli PBS, pH7.4.
Ugcino Yigcine phantsi kweemeko ezingakhuselekanga ku -20℃ ukuya -80℃ xa uyifumene.
Ncoma ukuba i-aliquot iprotheni ibe yimiyinge emincinci yokugcina eyona ilungileyo.

Ulwazi lweodolo

Igama lemveliso Ikati.Hayi Clone ID
Her2 AB0078-1 14-2
AB0078-2 15-6
AB0078-3 2-10

Qaphela: I-Bioantibody inokuhlengahlengiswa ngokwemfuno yakho.

Ucaphulo

1.Krawczyk N, et al.(2009) ubume be-HER2 kwiiseli zethumba ezisasazwayo emva konyango lwe-adjuvant lunokwahluka kwisimo sokuqala se-HER2 kwithumba eliphambili.I-Anticancer Res.29(10): 4019-24.


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