Anti-human GH Antibody, Monoclonal Mouse
Iinkcukacha zemveliso
Iinkcukacha zajikelele
I-hormone yokukhula (GH) okanye i-somatotropin, eyaziwa ngokuba yi-hormone yokukhula komntu (hGH okanye i-HGH), i-hormone ye-peptide ekhuthaza ukukhula, ukuveliswa kweeseli, kunye nokuvuselelwa kweeseli ebantwini nakwezinye izilwanyana.Ibalulekile ke ngoko kuphuhliso lomntu.I-GH iphinda ikhuthaze ukuveliswa kwe-IGF-1 kwaye inyuse i-concentration ye-glucose kunye ne-fatty acids yamahhala.Ludidi lwemitogen olukhethekileyo kuphela kwizamkeli kwiintlobo ezithile zeeseli.I-GH yi-191-amino acid, i-polypeptide ye-single-chain edityanisiweyo, igcinwe kwaye ikhutshwe ngamaseli e-somatotropic ngaphakathi kwamaphiko asecaleni kwi-pituitary gland yangaphambili.
Iimvavanyo ze-GH zisetyenziselwa ukuxilonga ukuphazamiseka kwe-GH, kuquka:
★ ukusilela kweGH.Ebantwaneni, i-GH ibalulekile ekukhuleni okuqhelekileyo kunye nophuhliso.Ukusilela kwe-GH kunokubangela ukuba umntwana akhule kancinci kwaye abe mfutshane kakhulu kunabantwana abakwiminyaka efanayo.Kubantu abadala, ukusilela kwe-GH kunokukhokelela ekuxineni kwamathambo kunye nokunciphisa ubunzima bemisipha.
★ Gigantism.Le yingxaki engaqhelekanga yobuntwana eyenza ukuba umzimba uvelise iGH eninzi kakhulu.Abantwana abane-gigantism bade kakhulu kwiminyaka yabo kwaye banezandla neenyawo ezinkulu.
★ Acromegaly.Le ngxaki, echaphazela abantu abadala, ibangela ukuba umzimba uvelise ihomoni eninzi yokukhula.Abantu abadala abane-acromegaly batyebe kunamathambo aqhelekileyo kunye nezandla ezikhulu, iinyawo kunye neempawu zobuso.
Iipropati
| Izindululo ezimbini | I-CLIA (Thatha-Ukufunyanwa): 7F5-2 ~ 8C7-10 |
| Ubunyulu | / |
| Ukuqulunqwa kwesithinteli | / |
| Ugcino | Yigcine phantsi kweemeko ezingakhuselekanga ku -20℃ ukuya -80℃ xa uyifumene. Ncoma ukuba i-aliquot iprotheni ibe yimiyinge emincinci yokugcina eyona ilungileyo. |
Ulwazi lweodolo
| Igama lemveliso | Ikati.Hayi | Clone ID |
| GH | AB0077-1 | 7F5-2 |
| AB0077-2 | 8C7-10 | |
| AB0077-3 | 2A4-1 | |
| AB0077-4 | 2E12-6 | |
| AB0077-5 | 6F11-8 |
Qaphela: I-Bioantibody inokuhlengahlengiswa ngokwemfuno yakho.
Ucaphulo
1. Ranabir S, Reetu K (Januwari 2011)."Uxinzelelo kunye namahomoni".Ijenali yaseIndiya ye-Endocrinology kunye neMetabolism.15 (1): 18–22.doi:10.4103/2230-8210.77573.PMC 3079864. PMID 21584161.
2. Greenwood FC, Landon J (Aprili 1966)."Ukukhuselwa kwehomoni ekuphenduleni uxinzelelo kumntu".Indalo.210 (5035): 540–1.Ikhowudi yebhayibhile:1966Natur.210..540G.doi:10.1038/210540a0.PMID 5960526. S2CID 1829264.
