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I-IL6 echasene nomntu, iMouse Monoclonal

Inkcazelo emfutshane:

Ukusulungekiswa I-Affinity-chromatography I-Isotype Akazimiselanga
Iintlobo zomamkeli Impuku Iintlobo Reactivity Umntu
Isicelo I-Chemiluminescent Immunoassay (CLIA)/ Immunochromatography (IC)

Iinkcukacha zeMveliso

Iithegi zeMveliso

Iinkcukacha zemveliso

Iinkcukacha zajikelele
I-Interleukin-6 (IL-6) i-cytokine ye-alpha-helical esebenzayo elawula ukukhula kweeseli kunye nokwahlulahlula kwezicubu ezahlukeneyo, eyaziwa ngokukodwa ngendima yayo kwi-immune response and reactions phase acute.Iprotheni ye-IL-6 ifihliwe ngeentlobo zeeseli ezibandakanya iiseli ze-T kunye ne-macrophages njenge-phosphorylated kunye ne-variable glycosylated molekyuli.Isebenzisa izenzo nge-receptor yayo ye-heterodimeric eyenziwe yi-IL-6R engenalo i-tyrosine / kinase domain kwaye ibophe i-IL-6 kunye nobudlelwane obuphantsi, kwaye ibonakaliswe kuyo yonke indawo i-glycoprotein 130 (gp130) ebopha i-IL-6.I-IL-6R eyinkimbinkimbi enobudlelwane obuphezulu kwaye ngaloo ndlela idlulisa iimpawu.I-IL-6 nayo ibandakanyeka kwi-hematopoiesis, i-metabolism yamathambo, kunye nokuqhubela phambili komhlaza, kwaye ichazwe njengendima ebalulekileyo ekulawuleni utshintsho olusuka kwi-innate ukuya kwi-immunity efunyenweyo.

Iipropati

Izindululo ezimbini I-CLIA (Thatha-Ukufunyanwa):
1B1-4 ~ 2E4-1
2E4-1 ~ 1B1-4
Ubunyulu >95%, igqitywe yiSDS-PAGE
Ukuqulunqwa kwesithinteli PBS, pH7.4.
Ugcino Yigcine phantsi kweemeko ezingakhuselekanga ku -20℃ ukuya -80℃ xa uyifumene.
Ncoma ukuba i-aliquot iprotheni ibe yimiyinge emincinci yokugcina eyona ilungileyo.

Uthelekiso lokukhuphisana

Uhlalutyo lonxulumano-<120pg>

iinkcukacha (1)

Uhlalutyo lokulungelelanisa -1.5-5000pg / mL

iinkcukacha (2)

Ulwazi lweodolo

Igama lemveliso Ikati.Hayi Clone ID
I-IL6 AB0001-1 1B1-4
AB0001-2 2E4-1
AB0001-3 2C3-1

Qaphela: I-Bioantibody inokuhlengahlengiswa ngokwemfuno yakho.

Ucaphulo

1.Zhong Z, Darnell ZW, Jr. Stat3: ilungu lentsapho ye-STAT eqhutywe yi-tyrosine phosphorylation ekuphenduleni i-epidermal factor factor and interleukin-6[J].Inzululwazi, ngo-1994.

2.J, Bauer, F, kunye nabanye.I-Interleukin-6 kunyango lwezonyango[J].I-Annals ye-Hematology, ngo-1991.


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