I-IL6 echasene nomntu, iMouse Monoclonal
Iinkcukacha zemveliso
Iinkcukacha zajikelele
I-Interleukin-6 (IL-6) i-cytokine ye-alpha-helical esebenzayo elawula ukukhula kweeseli kunye nokwahlulahlula kwezicubu ezahlukeneyo, eyaziwa ngokukodwa ngendima yayo kwi-immune response and reactions phase acute.Iprotheni ye-IL-6 ifihliwe ngeentlobo zeeseli ezibandakanya iiseli ze-T kunye ne-macrophages njenge-phosphorylated kunye ne-variable glycosylated molekyuli.Isebenzisa izenzo nge-receptor yayo ye-heterodimeric eyenziwe yi-IL-6R engenalo i-tyrosine / kinase domain kwaye ibophe i-IL-6 kunye nobudlelwane obuphantsi, kwaye ibonakaliswe kuyo yonke indawo i-glycoprotein 130 (gp130) ebopha i-IL-6.I-IL-6R eyinkimbinkimbi enobudlelwane obuphezulu kwaye ngaloo ndlela idlulisa iimpawu.I-IL-6 nayo ibandakanyeka kwi-hematopoiesis, i-metabolism yamathambo, kunye nokuqhubela phambili komhlaza, kwaye ichazwe njengendima ebalulekileyo ekulawuleni utshintsho olusuka kwi-innate ukuya kwi-immunity efunyenweyo.
Iipropati
| Izindululo ezimbini | I-CLIA (Thatha-Ukufunyanwa): 1B1-4 ~ 2E4-1 2E4-1 ~ 1B1-4 |
| Ubunyulu | >95%, igqitywe yiSDS-PAGE |
| Ukuqulunqwa kwesithinteli | PBS, pH7.4. |
| Ugcino | Yigcine phantsi kweemeko ezingakhuselekanga ku -20℃ ukuya -80℃ xa uyifumene. Ncoma ukuba i-aliquot iprotheni ibe yimiyinge emincinci yokugcina eyona ilungileyo. |
Uthelekiso lokukhuphisana
Uhlalutyo lonxulumano-<120pg>
Uhlalutyo lokulungelelanisa -1.5-5000pg / mL
Ulwazi lweodolo
| Igama lemveliso | Ikati.Hayi | Clone ID |
| I-IL6 | AB0001-1 | 1B1-4 |
| AB0001-2 | 2E4-1 | |
| AB0001-3 | 2C3-1 |
Qaphela: I-Bioantibody inokuhlengahlengiswa ngokwemfuno yakho.
Ucaphulo
1.Zhong Z, Darnell ZW, Jr. Stat3: ilungu lentsapho ye-STAT eqhutywe yi-tyrosine phosphorylation ekuphenduleni i-epidermal factor factor and interleukin-6[J].Inzululwazi, ngo-1994.
2.J, Bauer, F, kunye nabanye.I-Interleukin-6 kunyango lwezonyango[J].I-Annals ye-Hematology, ngo-1991.
