I-Anti-Human SHBG Antibody, iMouse Monoclonal
Iinkcukacha zemveliso
Iinkcukacha zajikelele
I-hormone yesondo ebopha i-globulin (SHBG) yi-glycoprotein malunga ne-80-100 kDa;inobudlelwane obuphezulu be-17 beta-hydroxysteroid hormones ezifana ne-testosterone kunye ne-estradiol.SHBG
Ukugxininiswa kwiplasma kulawulwa, phakathi kwezinye izinto, ibhalansi ye-androgen / estrogen, ihomoni yegilo, i-insulin kunye nezinto zokutya.Eyona nto ibaluleke kakhulu iprotheni yokuthutha i-estrogens kunye ne-androgens kwigazi le-peripheral.Ukugxininiswa kwe-SHBG yeyona nto iphambili elawula ukuhanjiswa kwazo phakathi kweprotein-bound and free states.Ugxininiso lwe-Plasma SHBG lu
echaphazelekayo ngenani lezifo ezahlukeneyo, amaxabiso aphezulu afunyenwe kwi-hyperthyroidism, i-hypogonadism, i-androgen insensitivity kunye ne-hepatic cirrhosis kumadoda.Ugxininiso oluphantsi lufumaneka kwi-myxoedma, i-hyperprolactinaemia kunye ne-syndromes yomsebenzi ogqithiseleyo we-androgen.Umlinganiselo we-SHBG uluncedo ekuvavanyeni ukuphazamiseka kancinci kwe-androgen metabolism kwaye yenza ukuba kuchongwe abo basetyhini abane-hirsutism ekunokwenzeka ukuba baphendule kunyango lwe-estrogen.
Iipropati
| Izindululo ezimbini | I-CLIA (Thatha-Ukufunyanwa): 3E10-1 ~ 3A10-5 3A10-5 ~ 3D8-2 |
| Ubunyulu | >95%, igqitywe yiSDS-PAGE |
| Ukuqulunqwa kwesithinteli | PBS, pH7.4. |
| Ugcino | Yigcine phantsi kweemeko ezingakhuselekanga ku -20℃ ukuya -80℃ xa uyifumene. Ncoma ukuba i-aliquot iprotheni ibe yimiyinge emincinci yokugcina eyona ilungileyo. |
Uthelekiso lokukhuphisana
Ulwazi lweodolo
| Igama lemveliso | Ikati.Hayi | Clone ID |
| SHBG | AB0030-1 | 3A10-5 |
| AB0030-2 | 3E10-1 | |
| AB0030-3 | 3D8-2 |
Qaphela: I-Bioantibody inokuhlengahlengiswa ngokwemfuno yakho.
Ucaphulo
1. I-Selby C. I-hormone yesondo ebopha i-globulin: imvelaphi, umsebenzi kunye nokubaluleka kweklinikhi.U-Ann Clin Biochem 1990; 27: 532-541.
2. Pugeat M, Crave JC, Tourniare J, et al.Uncedo lweklinikhi lwehomoni yesini ebopha umlinganiselo weglobulin.Horm Res 1996;45(3-5):148-155.
