Iinkcukacha zajikelele
I-MPO (i-myeloperoxidase) yi-enzyme ye-peroxidase efihliweyo yi-leukocytes esebenzayo edlala indima ye-pathogenic kwisifo senhliziyo, ngokukodwa ngokuqalisa ukungasebenzi kakuhle kwe-endothelial.I-Myeloperoxidase (MPO) yi-enzyme ebalulekileyo, enye yamacandelo e-antibacterial system kwi-neutrophils kunye ne-monocytes.I-MPO ithatha inxaxheba kwimpendulo yokuvuvukala kwiindawo ezininzi emzimbeni, kubandakanywa nezigulane ze-mammary.I-Myeloperoxidase (MPO), i-enzyme ethile ye-polymorphonuclear leukocyte, isetyenziswe ngaphambili ukulinganisa inani le-neutrophils kwizicubu.Umsebenzi we-MPO wafunyanwa uhambelana ngokuhambelana nenani leeseli ze-neutrophil.Inkqubo ye-MPO idlala indima ebalulekileyo ekulawuleni izifo kunye nokususwa kweeseli ezinobungozi.Nangona kunjalo, ukutshintshwa kwenkqubo ye-MPO kunokukhokelela kumonakalo we-DNA kunye ne-carcinogenesis.Iipolymorphisms kwi-MPO gene ziye zadibaniswa nokubonakaliswa okwandisiweyo kwe-MPO kunye nomngcipheko ophezulu wokuphuhliswa komhlaza.I-Myeloperoxidase (MPO) yenye yee-antigens ezijoliswe kuzo eziphambili ze-antineutrophil cytoplasmic autoantibodies (ANCA) ezifumaneka kwizigulane ezine-vasculitis encinci kunye ne-Pauci-immune necrotizing glomerulonephritis.I-Myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA) yi-autoantibody efumaneka rhoqo kwizigulane ezine-vasculitides.
Izindululo ezimbini | I-CLIA (Thatha-Ukufunyanwa): 4D12-3 ~ 2C1-8 4C16-1 ~ 2C1-8 |
Ubunyulu | >95%, igqitywe yiSDS-PAGE |
Ukuqulunqwa kwesithinteli | PBS, pH7.4. |
Ugcino | Yigcine phantsi kweemeko ezingakhuselekanga ku -20℃ ukuya -80℃ xa uyifumene. Ncoma ukuba i-aliquot iprotheni ibe yimiyinge emincinci yokugcina eyona ilungileyo. |
Igama lemveliso | Ikati.Hayi | Clone ID |
MPO | AB0007-1 | 2C1-8 |
AB0007-2 | 4D12-3 | |
AB0007-3 | 4C16-1 |
Qaphela: I-Bioantibody inokuhlengahlengiswa ngokwemfuno yakho.
1.Klebanoff, S. J.I-Myeloperoxidase: umhlobo kunye notshaba[J].J Leukoc Biol, 2005, 77 (5): 598-625.
2.Baldus, S. Myeloperoxidase Amanqanaba eSerum Aqikelela uMngcipheko kwizigulane ezine-Acute Coronary Syndromes[J].Ukujikeleza, 2003, 108(12): 1440.