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I-Anti-MPO Antibody, iMouse Monoclonal

Inkcazelo emfutshane:

Ukusulungekiswa I-Affinity-chromatography I-Isotype Akazimiselanga
Iintlobo zomamkeli Impuku Iintlobo Reactivity Umntu
Isicelo Immunochromatography (IC)/Chemiluminescent Immunoassay (CLIA)/Latex turbidimetric

Iinkcukacha zeMveliso

Iithegi zeMveliso

Iinkcukacha zemveliso

Iinkcukacha zajikelele
I-MPO (i-myeloperoxidase) yi-enzyme ye-peroxidase efihliweyo yi-leukocytes esebenzayo edlala indima ye-pathogenic kwisifo senhliziyo, ngokukodwa ngokuqalisa ukungasebenzi kakuhle kwe-endothelial.I-Myeloperoxidase (MPO) yi-enzyme ebalulekileyo, enye yamacandelo e-antibacterial system kwi-neutrophils kunye ne-monocytes.I-MPO ithatha inxaxheba kwimpendulo yokuvuvukala kwiindawo ezininzi emzimbeni, kubandakanywa nezigulane ze-mammary.I-Myeloperoxidase (MPO), i-enzyme ethile ye-polymorphonuclear leukocyte, isetyenziswe ngaphambili ukulinganisa inani le-neutrophils kwizicubu.Umsebenzi we-MPO wafunyanwa uhambelana ngokuhambelana nenani leeseli ze-neutrophil.Inkqubo ye-MPO idlala indima ebalulekileyo ekulawuleni izifo kunye nokususwa kweeseli ezinobungozi.Nangona kunjalo, ukutshintshwa kwenkqubo ye-MPO kunokukhokelela kumonakalo we-DNA kunye ne-carcinogenesis.Iipolymorphisms kwi-MPO gene ziye zadibaniswa nokubonakaliswa okwandisiweyo kwe-MPO kunye nomngcipheko ophezulu wokuphuhliswa komhlaza.I-Myeloperoxidase (MPO) yenye yee-antigens ezijoliswe kuzo eziphambili ze-antineutrophil cytoplasmic autoantibodies (ANCA) ezifumaneka kwizigulane ezine-vasculitis encinci kunye ne-Pauci-immune necrotizing glomerulonephritis.I-Myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA) yi-autoantibody efumaneka rhoqo kwizigulane ezine-vasculitides.

Iipropati

Izindululo ezimbini  
I-CLIA (Thatha-Ukufunyanwa):
4D12-3 ~ 2C1-8
4C16-1 ~ 2C1-8
Ubunyulu >95%, igqitywe yiSDS-PAGE
Ukuqulunqwa kwesithinteli PBS, pH7.4.
Ugcino Yigcine phantsi kweemeko ezingakhuselekanga ku -20℃ ukuya -80℃ xa uyifumene.
Ncoma ukuba i-aliquot iprotheni ibe yimiyinge emincinci yokugcina eyona ilungileyo.

Uthelekiso lokukhuphisana

iinkcukacha (1)
iinkcukacha (2)

Ulwazi lweodolo

Igama lemveliso Ikati.Hayi Clone ID
MPO AB0007-1 2C1-8
AB0007-2 4D12-3
AB0007-3 4C16-1

Qaphela: I-Bioantibody inokuhlengahlengiswa ngokwemfuno yakho.

Ucaphulo

1.Klebanoff, S. J.I-Myeloperoxidase: umhlobo kunye notshaba[J].J Leukoc Biol, 2005, 77 (5): 598-625.

2.Baldus, S. Myeloperoxidase Amanqanaba eSerum Aqikelela uMngcipheko kwizigulane ezine-Acute Coronary Syndromes[J].Ukujikeleza, 2003, 108(12): 1440.


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